Kenneth L Tyler Selected Research

Interleukin-6 (Interleukin 6)

11/2014	Activation of intrinsic immune responses and microglial phagocytosis in an ex vivo spinal cord slice culture model of West Nile virus infection.
4/2011	A brain slice culture model of viral encephalitis reveals an innate CNS cytokine response profile and the therapeutic potential of caspase inhibition.

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Kenneth L Tyler Research Topics

Disease

33	Infections 01/2021 - 03/2002
17	Encephalitis (Encephalitis, Rasmussen) 08/2020 - 11/2002
15	Reoviridae Infections 01/2019 - 03/2002
11	Virus Diseases (Viral Diseases) 01/2022 - 05/2004
8	West Nile Fever 01/2022 - 10/2009
8	acute flaccid myelitis 01/2021 - 10/2009
8	Progressive Multifocal Leukoencephalopathy 09/2013 - 01/2005
6	Viral Encephalitis 01/2019 - 04/2005
5	Central Nervous System Diseases (CNS Diseases) 02/2021 - 10/2004
5	Neuroinflammatory Diseases 01/2021 - 11/2014
5	Central Nervous System Infections (Central Nervous System Infection) 11/2014 - 07/2007
4	Meningitis 08/2020 - 02/2007
4	Inflammation (Inflammations) 01/2020 - 10/2009
4	Myelitis 01/2019 - 02/2007
4	Paralysis (Palsy) 01/2019 - 03/2008
3	Meningoencephalitis 02/2021 - 03/2010
3	Multiple Sclerosis 01/2019 - 01/2005
2	Rheumatoid Arthritis 01/2021 - 09/2011
2	Seizures (Absence Seizure) 01/2020 - 08/2013
2	Gliosis 01/2019 - 04/2005
2	Neoplasms (Cancer) 01/2016 - 01/2002
2	Herpes Simplex Encephalitis (Herpes Encephalitis) 09/2015 - 11/2014
2	Central Nervous System Viral Diseases 09/2013 - 04/2005
2	Nervous System Diseases (Neurological Disorders) 09/2011 - 11/2002
2	Myocarditis (Carditis) 08/2009 - 10/2004
2	Bell Palsy (Bell's Palsy) 02/2009 - 10/2007
1	Enterovirus Infections 01/2021
1	Disease Progression 01/2021
1	COVID-19 01/2020
1	Pneumonia (Pneumonitis) 01/2020
1	Alzheimer Disease (Alzheimer's Disease) 01/2020
1	Down Syndrome (Down's Syndrome) 01/2020
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2020
1	Viral Pneumonia 01/2020
1	Brain Edema (Cerebral Edema) 01/2019
1	Acute Disseminated Encephalomyelitis (Postinfectious Encephalomyelitis) 01/2019
1	Prodromal Symptoms 01/2019
1	Tick Bites 01/2019
1	Bites and Stings (Sting) 01/2017
1	Cognitive Dysfunction 01/2016
1	Varicella Zoster Virus Infection 01/2015

Drug/Important Bio-Agent (IBA)

11	Antiviral Agents (Antivirals)IBA 01/2019 - 01/2004
8	CytokinesIBA 01/2022 - 08/2009
7	Proteins (Proteins, Gene)FDA Link 11/2017 - 03/2002
6	Caspase 3 (Caspase-3)IBA 01/2019 - 10/2002
5	Biological ProductsIBA 01/2020 - 05/2004
5	CaspasesIBA 01/2014 - 10/2002
4	DNA (Deoxyribonucleic Acid)IBA 09/2011 - 11/2002
3	Rituximab (Mabthera)FDA Link 01/2021 - 03/2010
3	VaccinesIBA 01/2021 - 01/2010
3	Acyclovir (Aciclovir)FDA LinkGeneric 08/2020 - 01/2004
3	Fluoxetine (Prozac)FDA LinkGeneric 01/2019 - 05/2015
3	InterferonsIBA 01/2019 - 08/2012
3	Minocycline (Cyclops)FDA LinkGeneric 11/2017 - 04/2005
3	Caspase 8 (Caspase-8)IBA 01/2014 - 10/2002
3	Cytochromes c (Cytochrome c)IBA 04/2011 - 10/2002
3	Messenger RNA (mRNA)IBA 06/2009 - 11/2002
3	NF-kappa B (NF-kB)IBA 10/2005 - 01/2002
2	ChemokinesIBA 01/2022 - 11/2014
2	AutoantibodiesIBA 02/2021 - 01/2019
2	Glial Fibrillary Acidic ProteinIBA 02/2021 - 01/2019
2	Insect RepellentsIBA 01/2019 - 01/2017
2	Intravenous Immunoglobulins (IVIG)FDA Link 12/2017 - 04/2008
2	Valacyclovir (Valtrex)FDA LinkGeneric 09/2015 - 02/2009
2	Toll-Like Receptor 3IBA 11/2014 - 05/2004
2	Interleukin-6 (Interleukin 6)IBA 11/2014 - 04/2011
2	Glutamic Acid (Glutamate)FDA Link 03/2014 - 10/2009
2	Death Domain ReceptorsIBA 01/2014 - 01/2002
2	Caspase 9IBA 01/2014 - 10/2002
2	Anti-Bacterial Agents (Antibiotics)IBA 08/2013 - 01/2008
2	Viral AntigensIBA 07/2010 - 03/2008
2	JNK Mitogen-Activated Protein KinasesIBA 06/2009 - 07/2007
2	AntigensIBA 06/2009 - 04/2005
2	Immunoglobulin M (IgM)IBA 08/2008 - 08/2004
2	Phosphotransferases (Kinase)IBA 08/2007 - 03/2002
2	Natalizumab (Tysabri)FDA Link 07/2005 - 01/2005
1	PLX5622IBA 01/2022
1	PPAR gammaIBA 01/2021
1	Rosiglitazone (Avandia)FDA Link 01/2021
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2020
1	Interferon-betaIBA 01/2019
1	Immunoglobulin G (IgG)IBA 01/2019
1	Interferon-gamma (Interferon, gamma)IBA 01/2019
1	Oxygen (Dioxygen)IBA 01/2019
1	RNA (Ribonucleic Acid)IBA 01/2019
1	N-Acetylneuraminic Acid (Sialic Acid)IBA 01/2019
1	rho-Associated KinasesIBA 01/2019
1	Myelin-Oligodendrocyte GlycoproteinIBA 01/2019
1	Dexamethasone (Maxidex)FDA LinkGeneric 12/2017
1	Neutralizing AntibodiesIBA 12/2017
1	HIV hyperimmune globulinIBA 12/2017
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 11/2017
1	Immune Sera (Antisera)IBA 01/2017
1	pifithrinIBA 01/2016
1	Complement System Proteins (Complement)IBA 01/2016
1	Pharmaceutical PreparationsIBA 01/2015
1	Fingolimod Hydrochloride (FTY720)FDA Link 01/2015

Therapy/Procedure

25	Therapeutics 01/2022 - 01/2004
2	Drug Therapy (Chemotherapy) 01/2020 - 01/2002
2	Immunomodulation 09/2010 - 08/2009